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This anomaly is indicative of the larger challenge of culturing various microbial species, referred to as microbial “unculturability.” This cannot be explained by the use of agar alone or by the substitution of an alternative gelling agent, but rather by the difficulties in consistently recreating on an agar plate the multi-variable environment in which microbes grow naturally. Given such challenges, the risk of shortages, and the vulnerabilities of the agar supply chain, why is it so difficult to find suitable alternatives?
This leads to a poor developer experience, which pushes developers to only use WebAssembly when they absolutely need it. Oftentimes JavaScript is simpler and “good enough”. This means its users tend to be large companies with enough resources to justify the investment, which then limits the benefits of WebAssembly to only a small subset of the larger Web community.